Altered eye‐to‐foot coordination in standing parkinsonian patients during large gaze and whole‐body reorientations
Identifieur interne : 001814 ( Main/Exploration ); précédent : 001813; suivant : 001815Altered eye‐to‐foot coordination in standing parkinsonian patients during large gaze and whole‐body reorientations
Auteurs : Dimitri Anastasopoulos [Royaume-Uni, Grèce] ; Nafsica Ziavra [Royaume-Uni] ; Eugenia Savvidou [Grèce] ; Peter Bain [Royaume-Uni] ; Adolfo M. Bronstein [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 2011-10.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Adult, Aged, Biomechanical Phenomena, Coordination, Eye, Female, Fixation, Ocular (physiology), Foot, Gait Disorders, Neurologic (etiology), Gaze, Human, Humans, Inhibition (Psychology), Male, Middle Aged, Movement (physiology), Nervous system diseases, Orientation (physiology), Parkinson disease, Parkinson's disease, Parkinsonian Disorders (complications), Posture (physiology), Principal Component Analysis, Psychomotor Disorders (etiology), Reaction Time (physiology), bradykinesia, gaze, multisegmental coordination, turning.
- MESH :
- complications : Parkinsonian Disorders.
- etiology : Gait Disorders, Neurologic, Psychomotor Disorders.
- physiology : Fixation, Ocular, Movement, Orientation, Posture, Reaction Time.
- Adult, Aged, Biomechanical Phenomena, Eye, Female, Foot, Humans, Inhibition (Psychology), Male, Middle Aged, Principal Component Analysis.
Abstract
We investigated whether turning problems in Parkinson's disease may be the result of abnormal horizontal multisegmental angular coordination. Ten mildly affected patients and controls stood upright and voluntarily reoriented eyes and body to illuminated targets of eccentricities up to ±180 degrees. The effects of target location, visibility, and predictability on movement parameters were evaluated. Patients' latencies were normal. Control subjects foveated large eccentricity targets with a single gaze shift in approximately 30% of predictable trials. Patients rarely did so (10% of predictable trials) because of reduced head‐in‐space and trunk velocity. This resulted in massive foveation delays in patients—an average of half a second for displacements of 180 degrees. The covariation of eye, head, and trunk rotations was quantified statistically by means of principal components analysis. In both groups, the combined movement was initially stereotyped and two principal components accounted for nearly all data variance—the original three mechanical degrees of freedom (i.e., eye‐head‐trunk) are reduced to two kinematic degrees of freedom. However, in patients, the eye contributed more, and the head and trunk less, to the gaze shift than in control subjects. Although the eye‐to‐foot turning synergy is preserved in early‐stage parkinsonism, quantitative differences are prominent, particularly a larger ocular (and smaller head‐trunk) contribution in patients. Turning problems in Parkinson's disease do not result from inability to assemble multisegmental movements, as patients' ability to control numerous degrees of freedom is preserved. However, trunk bradykinesia reduces the frequency of single‐step gaze shifts, thus prolonging target acquisition time. Preserved eye motion compensates for trunk slowness. © 2011 Movement Disorder Society
Url:
DOI: 10.1002/mds.23798
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000001
- to stream Istex, to step Curation: 000001
- to stream Istex, to step Checkpoint: 000547
- to stream PubMed, to step Corpus: 001138
- to stream PubMed, to step Curation: 001138
- to stream PubMed, to step Checkpoint: 001480
- to stream Ncbi, to step Merge: 003290
- to stream Ncbi, to step Curation: 003290
- to stream Ncbi, to step Checkpoint: 003290
- to stream Main, to step Merge: 001868
- to stream PascalFrancis, to step Corpus: 000391
- to stream PascalFrancis, to step Curation: 002927
- to stream PascalFrancis, to step Checkpoint: 000719
- to stream Main, to step Merge: 001D09
- to stream Main, to step Curation: 001814
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Altered eye‐to‐foot coordination in standing parkinsonian patients during large gaze and whole‐body reorientations</title><author><name sortKey="Anastasopoulos, Dimitri" sort="Anastasopoulos, Dimitri" uniqKey="Anastasopoulos D" first="Dimitri" last="Anastasopoulos">Dimitri Anastasopoulos</name></author><author><name sortKey="Ziavra, Nafsica" sort="Ziavra, Nafsica" uniqKey="Ziavra N" first="Nafsica" last="Ziavra">Nafsica Ziavra</name></author><author><name sortKey="Savvidou, Eugenia" sort="Savvidou, Eugenia" uniqKey="Savvidou E" first="Eugenia" last="Savvidou">Eugenia Savvidou</name></author><author><name sortKey="Bain, Peter" sort="Bain, Peter" uniqKey="Bain P" first="Peter" last="Bain">Peter Bain</name></author><author><name sortKey="Bronstein, Adolfo M" sort="Bronstein, Adolfo M" uniqKey="Bronstein A" first="Adolfo M." last="Bronstein">Adolfo M. Bronstein</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3EE69A6A32D8CC5EAC7BFB1835D5AB28F69F85CE</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1002/mds.23798</idno><idno type="url">https://api.istex.fr/document/3EE69A6A32D8CC5EAC7BFB1835D5AB28F69F85CE/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000001</idno><idno type="wicri:Area/Istex/Curation">000001</idno><idno type="wicri:Area/Istex/Checkpoint">000547</idno><idno type="wicri:doubleKey">0885-3185:2011:Anastasopoulos D:altered:eye:to</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:21661049</idno><idno type="wicri:Area/PubMed/Corpus">001138</idno><idno type="wicri:Area/PubMed/Curation">001138</idno><idno type="wicri:Area/PubMed/Checkpoint">001480</idno><idno type="wicri:Area/Ncbi/Merge">003290</idno><idno type="wicri:Area/Ncbi/Curation">003290</idno><idno type="wicri:Area/Ncbi/Checkpoint">003290</idno><idno type="wicri:Area/Main/Merge">001868</idno><idno type="wicri:source">INIST</idno><idno type="RBID">Pascal:11-0481148</idno><idno type="wicri:Area/PascalFrancis/Corpus">000391</idno><idno type="wicri:Area/PascalFrancis/Curation">002927</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000719</idno><idno type="wicri:doubleKey">0885-3185:2011:Anastasopoulos D:altered:eye:to</idno><idno type="wicri:Area/Main/Merge">001D09</idno><idno type="wicri:Area/Main/Curation">001814</idno><idno type="wicri:Area/Main/Exploration">001814</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Altered eye‐to‐foot coordination in standing parkinsonian patients during large gaze and whole‐body reorientations</title><author><name sortKey="Anastasopoulos, Dimitri" sort="Anastasopoulos, Dimitri" uniqKey="Anastasopoulos D" first="Dimitri" last="Anastasopoulos">Dimitri Anastasopoulos</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Neuroscience, Imperial College London, Charing Cross Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Physiology and Clinical Neurophysiology, School of Nursing, University of Athens, Athens</wicri:regionArea><wicri:noRegion>Athens</wicri:noRegion></affiliation></author><author><name sortKey="Ziavra, Nafsica" sort="Ziavra, Nafsica" uniqKey="Ziavra N" first="Nafsica" last="Ziavra">Nafsica Ziavra</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Neuroscience, Imperial College London, Charing Cross Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Savvidou, Eugenia" sort="Savvidou, Eugenia" uniqKey="Savvidou E" first="Eugenia" last="Savvidou">Eugenia Savvidou</name><affiliation wicri:level="1"><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Physiology and Clinical Neurophysiology, School of Nursing, University of Athens, Athens</wicri:regionArea><wicri:noRegion>Athens</wicri:noRegion></affiliation></author><author><name sortKey="Bain, Peter" sort="Bain, Peter" uniqKey="Bain P" first="Peter" last="Bain">Peter Bain</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Neuroscience, Imperial College London, Charing Cross Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Bronstein, Adolfo M" sort="Bronstein, Adolfo M" uniqKey="Bronstein A" first="Adolfo M." last="Bronstein">Adolfo M. Bronstein</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Neuroscience, Imperial College London, Charing Cross Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-10">2011-10</date><biblScope unit="vol">26</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="2201">2201</biblScope><biblScope unit="page" to="2211">2211</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">3EE69A6A32D8CC5EAC7BFB1835D5AB28F69F85CE</idno><idno type="DOI">10.1002/mds.23798</idno><idno type="ArticleID">MDS23798</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Biomechanical Phenomena</term><term>Coordination</term><term>Eye</term><term>Female</term><term>Fixation, Ocular (physiology)</term><term>Foot</term><term>Gait Disorders, Neurologic (etiology)</term><term>Gaze</term><term>Human</term><term>Humans</term><term>Inhibition (Psychology)</term><term>Male</term><term>Middle Aged</term><term>Movement (physiology)</term><term>Nervous system diseases</term><term>Orientation (physiology)</term><term>Parkinson disease</term><term>Parkinson's disease</term><term>Parkinsonian Disorders (complications)</term><term>Posture (physiology)</term><term>Principal Component Analysis</term><term>Psychomotor Disorders (etiology)</term><term>Reaction Time (physiology)</term><term>bradykinesia</term><term>gaze</term><term>multisegmental coordination</term><term>turning</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Gait Disorders, Neurologic</term><term>Psychomotor Disorders</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Fixation, Ocular</term><term>Movement</term><term>Orientation</term><term>Posture</term><term>Reaction Time</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Biomechanical Phenomena</term><term>Eye</term><term>Female</term><term>Foot</term><term>Humans</term><term>Inhibition (Psychology)</term><term>Male</term><term>Middle Aged</term><term>Principal Component Analysis</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Coordination</term><term>Homme</term><term>Maladie de Parkinson</term><term>Oeil</term><term>Pathologie du système nerveux</term><term>Pied</term><term>Regard</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We investigated whether turning problems in Parkinson's disease may be the result of abnormal horizontal multisegmental angular coordination. Ten mildly affected patients and controls stood upright and voluntarily reoriented eyes and body to illuminated targets of eccentricities up to ±180 degrees. The effects of target location, visibility, and predictability on movement parameters were evaluated. Patients' latencies were normal. Control subjects foveated large eccentricity targets with a single gaze shift in approximately 30% of predictable trials. Patients rarely did so (10% of predictable trials) because of reduced head‐in‐space and trunk velocity. This resulted in massive foveation delays in patients—an average of half a second for displacements of 180 degrees. The covariation of eye, head, and trunk rotations was quantified statistically by means of principal components analysis. In both groups, the combined movement was initially stereotyped and two principal components accounted for nearly all data variance—the original three mechanical degrees of freedom (i.e., eye‐head‐trunk) are reduced to two kinematic degrees of freedom. However, in patients, the eye contributed more, and the head and trunk less, to the gaze shift than in control subjects. Although the eye‐to‐foot turning synergy is preserved in early‐stage parkinsonism, quantitative differences are prominent, particularly a larger ocular (and smaller head‐trunk) contribution in patients. Turning problems in Parkinson's disease do not result from inability to assemble multisegmental movements, as patients' ability to control numerous degrees of freedom is preserved. However, trunk bradykinesia reduces the frequency of single‐step gaze shifts, thus prolonging target acquisition time. Preserved eye motion compensates for trunk slowness. © 2011 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Grèce</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Anastasopoulos, Dimitri" sort="Anastasopoulos, Dimitri" uniqKey="Anastasopoulos D" first="Dimitri" last="Anastasopoulos">Dimitri Anastasopoulos</name></region><name sortKey="Bain, Peter" sort="Bain, Peter" uniqKey="Bain P" first="Peter" last="Bain">Peter Bain</name><name sortKey="Bronstein, Adolfo M" sort="Bronstein, Adolfo M" uniqKey="Bronstein A" first="Adolfo M." last="Bronstein">Adolfo M. Bronstein</name><name sortKey="Ziavra, Nafsica" sort="Ziavra, Nafsica" uniqKey="Ziavra N" first="Nafsica" last="Ziavra">Nafsica Ziavra</name></country><country name="Grèce"><noRegion><name sortKey="Anastasopoulos, Dimitri" sort="Anastasopoulos, Dimitri" uniqKey="Anastasopoulos D" first="Dimitri" last="Anastasopoulos">Dimitri Anastasopoulos</name></noRegion><name sortKey="Savvidou, Eugenia" sort="Savvidou, Eugenia" uniqKey="Savvidou E" first="Eugenia" last="Savvidou">Eugenia Savvidou</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001814 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001814 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:3EE69A6A32D8CC5EAC7BFB1835D5AB28F69F85CE
|texte= Altered eye‐to‐foot coordination in standing parkinsonian patients during large gaze and whole‐body reorientations
}}
| This area was generated with Dilib version V0.6.23. |  |